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G protein-coupled receptors (GPCR) represent the largest family of proteins expressed at the cell surface. GPCRs are involved in multiple physiological and pathological processes, and are targeted by 30-40% of currently prescribed drugs. Regardless of this fact, these drugs target only 10% of all GPCRs highlighting the great potential of this protein family for future drug design.

GPCR research is multi-disciplinary, dealing with numerous biological and pathological processes.  Accordingly, GPCR researchers often work in different fields and research organizations. To gather these different players in France, the “Groupement de Recherche” (GDR) 3545 on « G protein-coupled receptors – from physiology to drugs » has been founded by the CNRS in 2012.

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